Epitalon

Epitalon is a very special peptide. It can elongate teleromeres. The question is, what is a telomere? A telomere is part of a chromosome, which is where your DNA is stored. As we age, these telomeres start to shorten. The shortening of telomeres leads to senescence, apoptosis and cancer type transformation in cells. This affects the health and lifespan of an individual. Different things can lead to lengthening or shortening telomere length as we age. The ability to reduce the rate of telomere shortening can lead to a delayed onset of age-associated disease and increased lifespan. Epitalon works on telomerase enzymatic activity. Telomerase is the enzyme that elongates the telomere thus increasing the length of the telomere.

Helps:
-       Lengthen telomeres
-       Increase sleep quality
-       Possible cancer prevention

1.     Anisimov, V. A., et al. (2003). Effect of Epitalon on Biomarkers of Aging, Life span and Spontaneous Tumor Incidence in Female Swiss-derived SHR Mice. Biogerontology, 4(4):193-202. DOI: 10.1023/a:1025114230714
2.     Khavinson, V. (2002). Peptides and Ageing. Neuro Endocrinol Lett, Suppl 3:11-144
3.     Khavinson, V., Bondarev, I. E., & Butyugov, A. A. (2003). Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells. Bull Exp Biol Med, 135(6):590-2. DOI: 10.1023/a:1025493705728
4.     Khavinson, V., et al. (2020). AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism. Molecules, 25(3):609. DOI: 10.3390/molecules25030609
5.     Khavinson, V., et al. (2003). Peptide Epitalon activates chromatin at the old age. Neuro Endocrinol Lett, 24(5):329-33
6.     Shammas, M. A. (2012). Telomeres, Lifestyle, Cancer, and Aging. Curr Opin Clin Nutr Metab Care, 14(1):28–34. DOI: 10.1097/MCO.0b013e32834121b1