Melanotan I

Melanotan I works at creating more melanin in the skin. Melanin deposits act as a natural sunblock at the cellular level. Melanotan tanning injections may offer a way to bring upon a safe, cosmetic tan with less damage. Melanotan I is related to Melanotan II but is a shorter amino acid sequence. Melanotan I has a shorter half life of Melanotan II. Typically people need to dose Melanotan I twice daily.

-       Tanning
-       Vitaligo
-       Prevents skin from burning in UV light

1.     Dor, R. T. et al. (2004). Effects of a Superpotent Melanotropic Peptide in Combination with Solar UV Radiation on Tanning of the Skin in Human Volunteers. Arch Dermatol, 140(7):827-35. DOI: 10.1001/archderm.140.7.827
2.     Lim, H. W., et al. (2015). Afamelanotide and Narrowband UV-B Phototherapy for the Treatment of Vitiligo: A Randomized Multicenter Trial. AMA Dermatol, 151(1):42-50. DOI: 10.1001/jamadermatol.2014.1875
3.     Ugwu, S. O., et al. (1997). Skin Pigmentation and Pharmacokinetics of Melanotan-I in Humans. Biopharm Drug Dispos, 18(3):259-69. DOI: 10.1002/(sici)1099081x(199704)18:3<259::aid-bdd20>;2-x