Melanotan II

This peptide changes the melanin in the skin. The peptide works on what is called the alpha-melanocyte-stimulating hormone (alpha-MSH). People who start on this sunless tanning peptide find their melanin in their skin darkens with use. An increased exposure to sunlight will increase the production of melanin tremendously. The peptide PT-141 is a derivative of melanotan II. Therefore, some increased libido is seen while using melanotan II. Melanotan II helps protect the skin from burning by placing down more melanin, which acts as a natural sunblock.

-       Tanning
-       Weight loss
-       Libido
-       Vitaligo
-       Prevents skin from burning in UV light

1.     Dorr, R. T., et al. (1996). Evaluation of Melanotan-II, A Superpotent Cyclic Melanotropic Peptide in a Pilot Phase-I Clinical Study. Life Sci, 58(20):1777-84. DOI: 10.1016/0024-3205(96)00160-9
2.     Raposinho, P. D., White, R. B., & Auber, M. L. (2003). The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat. J Neuroendocrinol, 15(2):173-81. DOI: 10.1046/j.1365-2826.2003.00962.x
3.     Ter Laak, M. P., Brakkee, J. H., Adan, R. A. H., Hamers, F. P. T., & Gispen, W. H. (2003). The Potent Melanocortin Receptor Agonist Melanotan-II Promotes Peripheral Nerve Regeneration and has Neuroprotective Properties in the Rat. Eur J Pharmacol, 462(1-3):179-83.  DOI: 10.1016/s0014-2999(02)02945-x