NAD+ - $50
NAD+ is the precursor to all energy production in the body. It is what creates the cofactor for cellular energy. As we age, our levels of NAD+ become lower. Many age-associated disorders and diseases can be traced back to low levels of NAD+. Metabolic disorders, neurodegenerative diseases, and mental disorders all have been linked to these low levels. NAD+ biosynthesis has been targeted as an area that can treat or prevent these disease processes. The age-related disorders that can occur have been seen in studies to benefit from taking NAD+ intermediates such as nicotinamide mononucleotide and nicotinamide riboside. Both of these products can be taken orally but only IV NAD+ can be absorbed directly (Johnson). It has been well documented that NAD+ has a role in anti-aging and longevity. The NAD+ salvage pathway that creates NAD+ involves tryptophan (an amino acid) as a starting point. Other pathways that use tryptophan are serotonin and melatonin. These two molecules help with sleep, the gut, and mood. When more NAD+ production is needed such as in inflammation, tryptophan is diverted towards making more NAD+ and less serotonin and melatonin (Yaku). This molecule also plays a large role in skeletal muscle development. It helps with regeneration, aging, and disease. Higher levels of NAD+ have been found to be great at augmenting muscle health (Goody).
The shot is just a quick boost of NAD+. People who wish to do this daily may also purchase a bottle to take home and perform daily injections.
Goody, M. F., & Henry, C. A. (2018). A need for NAD+ in muscle development, homeostasis, and aging. Skelet Muscle, 8, 9. DOI: 10.1186/s13395-018-0154-1
Johnson, S., & Imai, S. (2018). NAD + biosynthesis, aging, and disease. F1000Res, 7: 132. DOI: 10.12688/f1000research.12120.1
Yaku, K., Okabe, K., & Nakagawa, T. NAD Metabolism: Implications in Aging and Longevity. Ageing Res Rev, 47, 1-17. DOI: 10.1016/j.arr.2018.05.006