Perineural Injection Thearpy (PIT)

This injection therapy is being used for the treatment of pain. It is a very easy and mildly invasive injection technique that can be used to help reduce pain. The idea is that all pain is derived from small nerve fibers around the body that are putting out signals to heal the body at the specific site of pain. Most neuropathic pain is associated with nerve entrapment causing local lack of blood supply. Utilizing glucose (sugar) water (dextrose 5%), the nerve inflammation can be brought under control through a receptor that removes sodium for sugar. As the sugar moves into the cell, sodium and also water, move out. This reduction in sodium and water allows the nerve to reduce in swelling. Once the nerve swelling has gone down, the body is allowed to heal the area that once had trauma.

Helps with:
-       Nerve pain
-       Chronic pain
-       Nerve healing
-       Sports injuries

1.     Chen, S., Shen, Y., Ho, T., Chen, L., Wu, Y. (2018). Ultrasound-guided Perineural Injection with Dextrose for Treatment of Radial Nerve Palsy. Medicine (Baltimore), 97(23): e10978. DOI: 10.1097/MD.0000000000010978
2.     Dahl, E. & Cohen, S. P. (2008). Perineural Injection of Etanercept as a Treatment for Postamputation Pain. Clin J Pain, 24(2):172-5. DOI: 10.1097/AJP.0b013e31815b32c8
3.     Shen, Y., et al. (2019). Comparison of Perineural Platelet-rich Plasma and Dextrose Injections for Moderate Carpal Tunnel Syndrome: A Prospective Randomized, Single-blind, Head-to-head Comparative Trial. J Tissue Eng Regen Med, 13(11):2009-2017. DOI: 10.1002/term.2950
4.     Thor, J. A.,  Hanapi, N. H. M., Halil, H., & Suhaimi, H. (2017). Perineural Injection Therapy in the Management of Complex Regional Pain Syndrome: A Sweet Solution to Pain. Pain Med, 18(10):2041-2045. DOI: 10.1093/pm/pnx063