Rough Morning - $190

This bag helps you recover from a night out drinking and over indulging. It comes packed with electrolytes, vitamins, minerals, anti-inflammatory medication and anti-nausea medication. This helps rehydrate and maintain energy levels.

Add on a glutathione to help the liver detox or dexamethasone to help drop that inflammation down even further.

Ingredients: Magnesium, B complex, B-12, ketoralac, ondansetron, vitamin C, MIC

Vitamin C – Vitamin C works in many metabolic pathways including activation of B vitamins, turning cholesterol into bile acids and creating serotonin in the body from a conversion of tryptophan. Vitamin C is a powerful antioxidant that is used to clean the body from free radical damage. The immune system needs vitamin C to function. It helps lower allergic reactions while also activating the immune defense systems to fight off infections. Vitamin C plays a large role in the body and has been studied in the use of cancer, diabetes, neurodegenerative disease, heavy metal toxicity and atherosclerosis (Chambial).

MIC
-       Methionine – Methionine regulates the metabolic processes, the innate immune system, and digestive functioning in humans. It also works on lipid metabolism. It activated antioxidant enzymes, decreases DNA damage and potentially carcinogenic processes (Martínez).
-       Inositol - Inositol supplementation may result in reduction in triglycerides, total- and LDL-cholesterol levels. It also lowers the fat around the liver (Tabrizi).
-       Choline – Choline has been found to rapidly reduce body mass without any changes to strength. Also, choline has been found to be helpful in fatty liver disease. Choline may also increase cognitive function (Elsawy).

B complex
-       B1 (thiamine) – this B vitamin is useful in glucose metabolism, heart failure, diabetes, pain-associated disease processes and neurodegenerative conditions (Małecka).
-       B2 (riboflavin) – the cellular energy mechanisms need riboflavin to function properly. Also, this vitamin helps the best antioxidant the body produces, glutathione, function properly (Pinto).
-       B3 (niacin) – Niacin plays a role in neuroprotection in the central nervous system. It also helps lower cholesterol, triglycerides, low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), and lipoprotein levels. It can increase high-density lipoprotein (HDL) cholesterol. It also reduces the incidence of cardiovascular events, helps in premature aging. It has been seen to be useful in neurological conditions. Circadian rhythm is also found to have a connection to this vitamin. Niacin is a precursor to NAD+, which has been studied for it’s anti-aging benefits (Jacobson).
-       B5 (pantothenic acid) – Wound healing has been found to be increased with this vitamin. Anti-microbial effects have also been seen with pantothenic acid. It improves wound healing post surgery. Studies have shown that when there is a deficiency in B5, reduced cortisol production can occur as well as an increase in pain from arthritis, fatigue, depression and insomnia. It is useful as an anti-inflammatory (Gheita).
-       B6 (Pyridoxine) – As a coenzyme, pyridoxine is found to be involved in over 100 enzyme reactions. Amino acid metabolism uses B6. Homocysteine (one of the major inflammatory signals related to heard disease) break down is aided by B6. Carbohydrate metabolism and fat metabolism both need this vitamin to properly work. It’s work as a potent antioxidant vitamin makes it useful for the body (Hellmann).

B12 – This essential vitamin is useful for metabolism, energy, fat loss, and suppressing the appetite. It is commonly touted as a great way to get extra energy (Wolffenbuttel).

Magnesium – This vitamin is needed for more than 300 different enzymatic activities in the body. It is critical for the body to make cellular energy. It is essential for the use of muscle contractions, which is why it acts as a potent muscle relaxer. Magnesium also works on blood pressure, insulin metabolism, and cardiac excitability. The transmission through the nervous system depends on magnesium as well as neuromuscular contractions. Since magnesium works on many different systems, it plays a large role in the prevention and treatment of multiple disease processes. Low levels of magnesium are found in alzheimer’s disease, insulin resistance, hypertension, stroke, heart disease, migraines, attention deficit hyperactivity disorder (ADHD) and type-2 diabetes. Typically in IV form, magnesium leads to the relaxed feeling that occurs during the therapy (Gröber).

Ketoralac – potent anti-inflammatory medication used for mild to moderate pain and aches

Ondansetron – anti-nausea medication

1.     Chambial, S., Dwivedi, S., Shukla, K. K., John, P. J., & Sharma, P. (2013). Vitamin C in Disease Prevention and Cure: An Overview. Indian J Clin Biochem., 28(4), 314–328. DOI: 10.1007/s12291-013-0375-3
2.     Elsawy, G., Abdelrahman, O., & Hamza, A. (2014). Effect of Choline Supplementation on Rapid Weight Loss and Biochemical Variables Among Female Taekwondo and Judo Athletes. J Hum Kinet, 40, 77–82. DOI: 10.2478/hukin-2014-0009
3.     Gheita , A.A., Gheita, T. A., & Kenawy, S. A. (2020). The Potential Role of B5: A Stitch in Time and Switch in Cytokine. Phytother Res, 34(2), 306-314. DOI: 10.1002/ptr.6537
4.     Hellmann , H. & Mooney, S. (2010). Vitamin B6: A Molecule for Human Health? Molecules, 15(1):442-59, DOI: 10.3390/molecules15010442
5.     Gröber, U., Schmidt, J., & Kisters, K. (2015). Magnesium in Prevention and Therapy. Nutrients, 7(9), 8199–8226. DOI: 10.3390/nu7095388
6.     Jacobson, M. K. & Jacobson, E. L. (2018). Vitamin B3 in Health and Disease: Toward the Second Century of Discovery. Methods Mol Biol, 1813, 3-8.  DOI: 10.1007/978-1-4939-8588-3_1
7.     Małecka, S. A., Poprawski, K., & Bilski, B. (2006). Prophylactic and Therapeutic Application of Thiamine (Vitamin B1)--a New Point of View. Wiad Lek, 59(5-6), 383-7.
8.     Martínez, Y. Li, X., Liu, G., Bin, P., Yan, W., Más, D., Valdivié, M., Hu, C. A., Ren, W., & Yin, Y. (2017). The Role of Methionine on Metabolism, Oxidative Stress, and Diseases. Amino Acids, 49(12), 2091-2098. DOI: 10.1007/s00726-017-2494-2
9.     Pinto, J. T. & Zempleni, J. (2016). Riboflavin. Adv Nutr, 7(5), 973–975. DOI: 10.3945/an.116.012716
10. Tabrizi, R., Ostadmohammadi, V., Lankarani, K. B., Peymani, P., Akbari, M., Kolahdooz, F., & Asemi, Z. (2018). The Effects of Inositol Supplementation on Lipid Profiles Among Patients with Metabolic Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Lipids Health Dis, 17, 123. DOI: 10.1186/s12944-018-0779-4
11. Wolffenbuttel, B. H. R., Wouters, H. J. C. M., Heiner-Fokkema, M. R., & van der Klauw, M. V. The Many Faces of Cobalamin (Vitamin B12) Deficiency. Mayo Clin Proc Innov Qual Outcomes, 3(2), 200–214. DOI: 10.1016/j.mayocpiqo.2019.03.002