What are the benefits longevity peptides?

GHK-cu
This combination of peptides repairs skin and reduces fine lines and wrinkles. It is also used for hair growth in clients. The Argireline and Leuphasyl combination add in botox like effects with the ability to reduce fine lines and wrinkles by ~30% in 30 days (Lim). GHK-cu is a great peptide not only for skin but also for it’s ability to help with wound healing. It is used often topically for the face or other areas to reduce wrinkles. It can help with hyperpigmentation or UV radiation damage. Though, it is hypothesized that CHK-cu can also help with age-related cognitive decline when used as an injectable (Pickart).

Helps with:
– Improves elasticity
– Tightens skin in clinical studies
– Improves skin density and firmness
– Improves photo-damage and hyperpigmentation
– Reduces fine lines and wrinkles
– Improve skin clarity
– Increases keratinocyte production
– Reverses thinning skin
– Repairs skin
– Helps smooth rough skin
– Protects skin from the harmful UV radiation
– Increases hair growth, thickness and enlarges hair follicle size
– Anti-oxidant and anti-inflammatory
– Possibly age-associated neurodegeneration and cognitive decline
– Reset genes of diseased cells from patients with cancer or COPD to a more healthy state
– Suppress fibrinogen synthesis
– Activates genes of DNA repair
– Activates genes of the antioxidant system

Epitalon
Epitalon is a very special peptide. It can elongate teleromeres. The question is, what is a telomere? A telomere is part of a chromosome, which is where your DNA is stored. As we age, these telomeres start to shorten. The shortening of telomeres leads to senescence, apoptosis and cancer type transformation in cells. This affects the health and lifespan of an individual. Different things can lead to lengthening or shortening telomere length as we age. The ability to reduce the rate of telomere shortening can lead to a delayed onset of age-associated disease and increased lifespan. Epitalon works on telomerase enzymatic activity. Telomerase is the enzyme that elongates the telomere thus increasing the length of the telomere.

Helps:
– Lengthen telomeres
– Increase sleep quality
– Possible cancer prevention

Thymosin Alpha 1
Thymosin alpha 1 (TA1) is an immune modulating peptide, or small protein molecule. It is naturally occurring in the thymus gland. The thymus gland is where the T cell (part of the immune response) matures. The T cell is released when TA1 levels are increased. As we age, the levels of TA1 decrease. Some of the symptoms of deficiency are: fatigue, lack of motivation, physical exhaustion, chronic infections, slow wound healing, joint pain/injury. Helping the immune system could be considered helping longevity. This peptide really helps with overall immune functioining and could be useful for everyone.

Thymosin Alpha 1 helps the immune system:
– Enhances the way the T Cells function. The T Cells are part of the immune system and are given the responsibility of killing targeted pathogens that enter the body
– Rids the body of senescent cells that may lead to cancer growth
– Clears up active and chronic infections
– Anti-fungal, anti-bacterial and anti-viral properties
– Helps to fight seasonal allergies
– Protects against oxidative damage
– Promotes Th2-Th1 shift decreasing inflammation and increasing ability to fight intracellular infections
– Stimulate production of anti-inflammatory cytokines
– Increases NK cell maturation and activity

Helps with:
– Autoimmune thyroiditis
– Eczema
– Asthma
– Rheumatoid arthritis
– Inflammatory bowel disease (UC/CD)
– May induce contrasting effects in different tissues and different immunologic situations
– Lyme/CFS/FM: Reverses immune suppressive/evasive effects of Lyme
– COPD
– Antifungal
– Increases antioxidants, including glutathione production
– Inhibits viral replication
– Increases expression of viral antigens on the surface of infected cells (HIV, HBV, HSV)
– Blocks steroid-induced apoptosis of thymocytes

Studies on TA1 have shown it to be significantly lower in chronic inflammatory autoimmune disease (Pica). TA1 has been found to stimulate the immune system. This peptide shows utility in treatment for immune suppression, whether related to aging or to diseases such as infection or cancer (King). The ability to modulate the immune system and up regulate or down regulate different aspects has also been seen. It is currently being studied for treatment in melanoma and breast cancer (Wang). Recently, it has been found to be useful in treatment of severe COVID-19 cases with a reduction of mortality (Liu).